Help with Nutrition Final

Question by Siddiqui101 Reward: 25 Pond Points + 10 Knowledge Tokens Status: Pending a resolution
Which of the following is required for the absorption of Vitamin B12
a. Bile
b. Lipase
c. Intrinsic factor
d. Carboxy peptidase



Reply from MikeBrWade User Rating:  120 Knowledge Tokens
B
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Reply from MikeBrWade User Rating:  120 Knowledge Tokens
Whoops, my medical knowlage is rusty... out of my books.

The free B-12 then attaches to gastric intrinsic factor, which is generated by the gastric parietal cells in response to histamine, gastrin and pentagastrin, as well as the presence of food. The generation of this intrinsic factor-B12 complex will allow absorption of the vitamin as well as protect the vitamin from catabolism by intestinal bacteria. If this step fails due to gastric parietal cell atrophy (the problem in pernicious anemia), sufficient B-12 is not absorbed later on, unless administered orally in relatively massive doses (500 to 1000 mcg/day). Due to the complexity of B-12 absorption, geriatric patients, many of whom are hypoacidic due to reduced parietal cell function, have an increased risk of B-12 deficiency

so C
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Reply from MikeBrWade User Rating:  120 Knowledge Tokens
Just FYI my to clarify my first response, where I was wrong HA:

A lipase is a water-soluble enzyme that catalyzes the hydrolysis of ester bonds in waterinsoluble, lipid substrates. Lipases thus comprise a subclass of the esterases.

Lipases perform essential roles in the digestion, transport and processing of dietary lipids (e.g. triglycerides, fats, oils) in most- if not all- living organisms. Genes encoding lipases are even present in certain viruses.
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